ChitoSponge is an absorbable hemostatic sponge prepared from gelatin, that stops bleeding effectively and rapidly during all surgeries.
Main component:
Gelatin
Features and benefits :
Hemostasis less than 2 minutes
Antibacterial
Biocompatible:
No cell toxicity (ISO 10993-5)
No any genotoxicity (1)
No skin irritation, no sensitivity (ISO 10993-10)
Ready to use
Mechanism of action:
When the ChitoSponge applied to bleeding site, it absorbs blood due to its porous structure. On the other hand, as soon as the blood comes in contact with the ChitoSponge, the platelets are activated, resulting in the formation of clots and the acceleration of homeostasis by releasing various factors. The sponge matrix changes to gel, which covers bleeding sites tightly.
Instruction of use:
1- Place a sufficient amount of ChitoSponge on the bleeding site and hold it in place with moderate pressure until hemostasis is achieved.
2- Once hemostasis is achieved, any excess ChitoSponge should be carefully removed.
Application:
Abdominal and Spleen Surgery,
Parenchymal tissue surgery and liver biopsy,
Orthopedic Surgery,
Neuro Surgery,
Anorectal and Urology Surgery,
Gynecological surgery,
ENT Surgery
Stopping tumor bleeding;
Stopping aortic bleeding;
Stopping fistula bleeding during dialysis;
Stopping bleeding in hard-to-reach places
Warnings:
Avoid using ChitoSponge for implantation in bone defects, such as fractures.
Although ChitoSponge is an antibacterial hemostatic product, it is not intended to be used as a substitute for systemically administered therapeutic or prophylactic
antimicrobial agents to control or to prevent postoperative infections.
ChitoSponge should not be resterilized.
In vitro & in vivo tests >
Reference:
1. Elisabettacenni, Ciapetti, G., Stea, S., Corradini, A. and Carozzi, F., 2000. Biocompatibility and performance in vitro of a hemostatic gelatin sponge. Journal of Biomaterials Science, Polymer Edition, 11(7), pp.685-699.