ChitoSponge is a water-insoluble, porous, pliable, absorbable product. Hemostatic sponge prepared from bovine gelatin, that stops bleeding effectively and rapidly in surgeries.
Main component:
Bovine Gelatin
Features and benefits:
Hemostasis less than 2 minutes
Antibacterial
Ready to use
Biocompatible:
No cell toxicity according to ISO 10993-5
No any genotoxicity (1)
No skin irritation, no sensitivity according to ISO 10993-10
Mechanism of action:
When ChitoSponge applied to bleeding site, it absorbs blood due to its porous structure and accelerate the process of clotting. On the other hand, as soon as the blood comes in contact with the ChitoSponge, the platelets are activated, resulting in the formation of clots and the acceleration of homeostasis by releasing various clotting proteins. The sponge matrix following absorbing blood and other body fluids becomes gelified. changes to gel, which covers bleeding sites tightly.
Instruction of use:
1- Place a sufficient amount of ChitoSponge on the bleeding site and hold it in place with moderate pressure until hemostasis is achieved.
2- Once hemostasis is achieved, any excess ChitoSponge should be carefully removed.
Indications:
Abdominal and Spleen Surgery,
Parenchymal tissue surgery and liver biopsy,
Orthopedic Surgery,
Neuro Surgery,
Anorectal and Urology Surgery,
Gynecological surgery,
ENT Surgery
Stopping tumor bleeding;
Stopping aortic bleeding;
Stopping fistula bleeding during dialysis;
Stopping bleeding in hard-to-reach places
Contraindications:
Avoid using ChitoSponge for implantation in bone defects, such as fractures.
The use of ChitoSponge is not recommended in presence of infection.
Although ChitoSponge is an antibacterial hemostatic product, it is not intended to be used as a substitute for systemically administered therapeutic or prophylactic antimicrobial agents to control or to prevent postoperative infections.
ChitoSponge should not be resterilized.
In vitro & in vivo tests >
Reference:
1. Elisabettacenni, Ciapetti, G., Stea, S., Corradini, A. and Carozzi, F., 2000. Biocompatibility and performance in vitro of a hemostatic gelatin sponge. Journal of Biomaterials Science, Polymer Edition, 11(7), pp.685-699.